FocusHeuristics – expression-data-driven network optimization and disease gene prediction
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چکیده
منابع مشابه
FocusHeuristics – expression-data-driven network optimization and disease gene prediction
To identify genes contributing to disease phenotypes remains a challenge for bioinformatics. Static knowledge on biological networks is often combined with the dynamics observed in gene expression levels over disease development, to find markers for diagnostics and therapy, and also putative disease-modulatory drug targets and drugs. The basis of current methods ranges from a focus on expressio...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/srep42638